Publications
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- #39
- Decor: Delegated Computation on Randomness for Secure Evaluation of Nonlinear Functions
- Haris Smajlović, Kyle Sheng, Timos Antonopoulos, Ruzica Piskac, Hyunghoon Cho
- IEEE Security and Privacy (S&P)
- 2026
- Link
- #38
- Privacy-Enhancing Sequential Learning under Heterogeneous Selection Bias in Multi-Site EHR Data
- Ritoban Kundu, Maxwell Salvatore, Kumar Kshitij Patel, Lucila Ohno-Machado, Hyunghoon Cho, Xu Shi, Bhramar Mukherjee
- Journal of the American Medical Informatics Association
- 2026
- Link
- #37
- Memorization in Large Language Models in Medicine Prevalence Characteristics and Implications
- Anran Li, Lingfei Qian, Mengmeng Du, Yu Yin, Yan Hu, Zihao Sun, Yihang Fu, Hyunjae Kim, Erica Stutz, Xuguang Ai, Qianqian Xie, Rui Zhu, Jimin Huang, Yifan Yang, Siru Liu, Yih-Chung Tham, Lucila Ohno-Machado, Hyunghoon Cho, Zhiyong Lu, Hua Xu, Qingyu Chen
- Nature Communications
- 2026
- Link
- #36
- GOPHER: Optimization-based Phenotype Randomization for Genome-Wide Association Studies with Differential Privacy
- Anupama Nandi, Seth Neel, Hyunghoon Cho
- RECOMB
- 2026
- Link
- Best Paper Award
- #35
- Generating Synthetic Electronic Health Record (EHR) Data: A Review with Benchmarking
- Xingran Chen, Zhenke Wu, Xu Shi, Hyunghoon Cho, Bhramar Mukherjee
- Journal of the American Medical Informatics Association
- 2025
- Link
- #34
- Shechi: A Secure Distributed Computation Compiler Based on Multiparty Homomorphic Encryption
- Haris Smajlović, David Froelicher, Ariya Shajii, Bonnie Berger, Hyunghoon Cho, Ibrahim Numanagić
- USENIX Security
- 2025
- Link
- #33
- TX-Phase: Secure Phasing of Private Genomes in a Trusted Execution Environment
- Natnatee Dokmai, Kaiyuan Zhu, S. Cenk Sahinalp, Hyunghoon Cho
- Genome Research
- 2025
- Link
- Also appeared in RECOMB 2025
- #32
- Secure and Federated Genome-Wide Association Studies for Biobank-Scale Datasets
- Hyunghoon Cho, David Froelicher, Jeffrey Chen, Manaswitha Edupalli, Apostolos Pyrgelis, Juan R. Troncoso-Pastoriza, Jean-Pierre Hubaux, Bonnie Berger
- Nature Genetics
- 2025
- Link
- #31
- Learning-Augmented Sketching Offers Improved Performance for Privacy Preserving and Secure GWAS
- Junyan Xu, Kaiyuan Zhu, Jieling Cai, Can Kockan, Natnatee Dokmai, Hyunghoon Cho, David P. Woodruff, S. Cenk Sahinalp
- iScience
- 2025
- Link
- #30
- Privacy of Single-Cell Gene Expression Data
- Hyunghoon Cho
- Patterns
- 2024
- Link
- Invited Preview article for Walker et al. (Cell, 2024)
- #29
- Privacy-Enhancing Technologies in Biomedical Data Science
- Hyunghoon Cho, David Froelicher, Natnatee Dokmai, Anupama Nandi, Shuvom Sadhuka, Matthew M. Hong, Bonnie Berger
- Annual Review of Biomedical Data Science
- 2024
- Link
- #28
- Secure Discovery of Genetic Relatives across Large-Scale and Distributed Genomic Datasets
- Matthew Man-Hou Hong, David Froelicher, Ricky Magner, Victoria Popic*, Bonnie Berger*, Hyunghoon Cho*
- Genome Research
- 2024
- Link
- Best Student Paper Award at RECOMB 2024
- #27
- Reconstruction of Private Genomes Through Reference-Based Genotype Imputation
- Matthew J. Mosca and Hyunghoon Cho
- Genome Biology
- 2023
- Link
- #26
- Assessing Transcriptomic Re-Identification Risks Using Discriminative Sequence Models
- Shuvom Sadhuka, Daniel Fridman, Bonnie Berger*, Hyunghoon Cho*
- Genome Research
- 2023
- Link
- Also appeared in RECOMB 2023
- #25
- sfkit: A Web-Based Toolkit for Secure and Federated Genomic Analysis
- Simon Mendelsohn, David Froelicher, Denis Loginov, David Bernick, Bonnie Berger*, Hyunghoon Cho*
- Nucleic Acids Research
- 2023
- Link
- #24
- Scalable and Privacy-Preserving Federated Principal Component Analysis
- David Froelicher*, Hyunghoon Cho*, Manaswitha Edupalli, Joao Sa Sousa, Jean-Philippe Bossuat, Apostolos Pyrgelis, Juan Troncoso-Pastoriza, Bonnie Berger, Jean-Pierre Hubaux
- IEEE Security and Privacy (S&P)
- 2023
- Link
- #23
- Sequre: A High-Performance Framework for Secure Multiparty Computation Enables Biomedical Data Sharing
- Haris Smajlović, Ariya Shajii, Bonnie Berger, Hyunghoon Cho, Ibrahim Numanagić
- Genome Biology
- 2023
- Link
- Also appeared in IEEE HiCOMB 2022
- #22
- k-SALSA: k-Anonymous Synthetic Averaging of Retinal Images via Local Style Alignment
- Minkyu Jeon, Hyeonjin Park, Hyunwoo Kim, Michael Morley, Hyunghoon Cho
- ECCV
- 2022
- Link
- #21
- Secure and Federated Linear Mixed Model Association Tests
- Jeffrey Chen, Manaswitha Edupalli, Bonnie Berger*, Hyunghoon Cho*
- RECOMB Privacy Workshop
- 2022
- Link
- #20
- Mechanisms for Hiding Sensitive Genotypes with Information-Theoretic Privacy
- Fangwei Ye, Hyunghoon Cho, Salim El Rouayheb
- IEEE Transactions on Information Theory
- 2022
- Link
- Also appeared in ISIT 2020
- #19
- Truly Privacy-Preserving Federated Analytics for Precision Medicine with Multiparty Homomorphic Encryption
- David Froelicher, Juan R. Troncoso-Pastoriza, Jean Louis Raisaro, Michel A. Cuendet, Joao Sa Sousa, Hyunghoon Cho, Bonnie Berger, Jacques Fellay, Jean-Pierre Hubaux
- Nature Communications
- 2021
- Link
- #17
- Privacy-Preserving Genotype Imputation in a Trusted Execution Environment
- Natnatee Dokmai, Can Kockan, Kaiyuan Zhu, Xiaofeng Wang, S. Cenk Sahinalp* and Hyunghoon Cho*
- Cell Systems
- 2021
- Link
- Also appeared in RECOMB 2021
- #15
- Contact Tracing Mobile Apps for COVID-19: Privacy Considerations and Related Trade-offs
- {Hyunghoon Cho, Daphne Ippolito, Yun William Yu}
- arXiv
- 2020
- Link
- >580 citations (as of Sep 2025)
- #14
- Privacy-Preserving Biomedical Database Queries with Optimal Privacy-Utility Trade-offs
- Hyunghoon Cho*, Sean Simmons*, Ryan Kim, Bonnie Berger
- Cell Systems
- 2020
- Link
- Also appeared in RECOMB 2020
- #12
- Emerging Technologies Towards Enhancing Privacy in Genomic Data Sharing
- Bonnie Berger*, Hyunghoon Cho*
- Genome Biology
- 2019
- Link
- #9
- Realizing Private and Practical Pharmacological Collaboration
- Brian Hie*, Hyunghoon Cho*, Bonnie Berger
- Science
- 2018
- Link
- #7
- Secure Genome-wide Association Analysis Using Multiparty Computation
- Hyunghoon Cho, David J. Wu, Bonnie Berger
- Nature Biotechnology
- 2018
- Link
- Featured in Editors' Choice, Science and MIT News